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The Fetal Diagnosis and Treatment Committee has identified the following literature reviews to help identify best-practice and appropriate standards for clinical management of pediatric surgical disease.

If you have questions, contact Shinjiro Hirose.

Earn MOC CME from the Literature Reviews

Continuing medical education maintenance of certification self-assessment credit is now available for the Cancer, Critical Care, Ethics, Fetal, Outcomes and Trauma literature reviews.

  • ExPERT subscribers: log onto ExPERT, go to Pre-Created courses, look for “Articles” under course type and select the desired course. Remember to use Chrome or Safari.
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    *Subscriptions purchased prior to October 1 expire December 31. Subscriptions purchased October 1 or later expire December 31. 

Literature Reviews

Visual abstracts offer a quick snapshot of the articles.  Follow APSA on Facebook and Twitter.

Anhydramnios in the Setting of Renal Malformations: The National Institutes of Health Workshop Summary
Moxey-Mims et al. Obstet Gynecol. 2018 Jun;131(6):1069-1079.
PMID: 29742659
Anhydramnios is a lack of amniotic fluid surrounding the developing fetus defined as the deepest pocket of amniotic fluid measuring two cm or less in the second trimester. Anhydramnios due to fetal renal or urinary tract anomalies can result in severe pulmonary hypoplasia upon delivery. Amnioinfusion to restore amniotic fluid volume in pregnant women who carry a fetus with such anomalies may be a way to prevent pulmonary hypoplasia. This paper is a summary of a meeting of a panel of experts to further discuss this topic and to suggest an appropriate path to obtain meaningful research on the subject.

Ethical Considerations Concerning Amnioinfusions for Treating Fetal Bilateral Renal Agenesis
Sugarman et al. Obstet Gynecol 2018;131(1):130-134
PMID 29215523

Legal and Ethical Issues in Fetal Surgery
Dickens BM1, Cook RJ
Int J Gynaecol Obstet. 2011 Oct;115(1):80-3. 
PMID: 21839453

Weighing the Social and Ethical Considerations of Maternal-Fetal Surgery
Antiel RM1,2,3, Flake AW1, Collura CA2,4, Johnson MP1, Rintoul NE1, Lantos JD5, Curlin FA6, Tilburt JC2,7, Brown SD8, Feudtner C9.
Pediatrics. 2017 Dec;140(6). pii: e20170608
PMID: 29101225 

Ethical Challenges in the New World of Maternal-Fetal Surgery
Antiel RM
Semin Perinatol. 2016 Jun;40(4):227-33. doi
PMID: 26804036 

Prevalence, Correlates, and Outcomes of Omphalocele in the United States, 1995-2005.
Marshall J1, Salemi JL, Tanner JP, Ramakrishnan R, Feldkamp ML, Marengo LK, Meyer RE, Druschel CM, Rickard R, Kirby RS; National Birth Defects Prevention Network.
Obstet Gynecol. 2015 Aug;126(2):284-93.
PMID: 26241416 

Fetal MRI-Calculated Total Lung Volumes in the Prediction of Short-Term Outcome in Giant Omphalocele: Preliminary Findings.
Danzer E, Victoria T, Bebbington MW, Siegle J, Rintoul NE, Johnson MP, Flake AW, Adzick NS, Hedrick HL.
Fetal Diagn Ther. 2012;31(4):248-53.
PMID: 22572017 

Management of Giant Omphaloceles: A Systematic Review of Methods of Staged Surgical vs. Nonoperative Delayed Closure.
Bauman B, Stephens D, Gershone H, Bongiorno C, Osterholm E, Acton R, Hess D, Saltzman D, Segura B.
J Pediatr Surg. 2016 Oct;51(10):1725-30
PMID: 27570242 

Giant Omphaloceles: Surgical Management and Perinatal Outcomes.
Akinkuotu AC, Sheikh F, Olutoye OO, Lee TC, Fernandes CJ, Welty SE, Ayres NA, Cass DL.
J Surg Res. 2015 Oct;198(2):388-92.
PMID: 25918004 

Prenatal Steroids for Microcystic Congenital Cystic Adenomatoid Malformations
Curran PF, Jelin EB, Rand L, Hirose S, Feldstein VA, Goldstein RB, Lee H.
J Pediatr Surg. 2010 Jan;45(1):145-50.
PMID: 20105595

Cystic Adenomatoid Malformation Volume Ratio Predicts Outcome in Prenatally Diagnosed Cystic Adenomatoid Malformation of the Lung
Crombleholme TM, Coleman B, Hedrick H, Liechty K, Howell L, Flake AW, Johnson M, Adzick NS.
J Pediatr Surg. 2002 Mar;37(3):338-8.
PMID: 11877643

Congenital Lung Malformations: Informing Best Practice
Baird R, Puligandla PS, Laberge JM.
Semin Pediatr Surg. 2014 Oct; 23(5):270-7.
PMID: 25459011

Additional information regarding the prenatal diagnosis, prognosis, management and post-natal management of common fetal anomalies can be obtained within individual Not a Textbook (NaT) chapters, accessible for purchase via the APSA ExPERT platform  as well as in the APSA handbook: Fetal Diagnosis and Therapy, A Reference Handbook for Pediatric Surgeons which is available for download for APSA members.

Gastroschisis outcomes in North America: a comparison of Canada and the United States
Youssef F, Cheong LH, Emil S; Canadian Pediatric Surgery Network (CAPSNet).
J Pediatr Surg. 2016 Jun;51(6):891-5. doi: 10.1016/j.jpedsurg.2016.02.046. Epub 2016 Mar 3.
PMID: 27004440

Delivery planning for pregnancies with gastroschisis: findings from a prospective national registry
Al-Kaff A, MacDonald SC, Kent N, Burrows J, Skarsgard ED, Hutcheon JA; Canadian Pediatric Surgery Network.
Am J Obstet Gynecol. 2015 Oct;213(4):557.e1-8. doi: 10.1016/j.ajog.2015.06.048. Epub 2015 Jun 24.
PMID: 26116872

Effect of gestational age at birth on neonatal outcomes in gastroschisis
Carnaghan H, Baud D, Lapidus-Krol E, Ryan G, Shah PS, Pierro A, Eaton S.
J Pediatr Surg. 2016 May;51(5):734-8. doi: 10.1016/j.jpedsurg.2016.02.013. Epub 2016 Feb 11.
PMID: 26932253

Prenatal management of the fetus with isolated congenital diaphragmatic hernia in the era of the TOTAL trial
Deprest J, Brady P, Nicolaides K, Benachi A, Berg C, Vermeesch J, Gardener G, Gratacos E.
Semin Fetal Neonatal Med. 2014 Dec; 19(6):338-48.
PMID: 25447987 [PubMed – indexed for MEDLINE]

Observed to expected lung area to head circumference ratio in the prediction of survival in fetuses with isolated diaphragmatic hernia
Jani J, Nicolaides KH, Keller RL, Benachi A, Peralta CF, Favre R, Moreno O, Tibboel D, Lipitz S, Eggink A, Vaast P, Allegaert K, Harrison M, Deprest J; Antenatal-CDH-Registry Group.
Ultrasound Obstet Gynecol. 2007 Jul;30(1):67-71.
PMID: 17587219 [PubMed – indexed for MEDLINE]

Use of magnetic resonance imaging in prenatal prognosis of the fetus with isolated left congenital diaphragmatic hernia
Victoria , Bebbington MW, Danzer E, Flake AW, Johnson MP, Dinan D, Adzick NS, Hedrick HL.
Prenat Diagn. 2012 Aug;32(8):715-23. doi: 10.1002/pd.3890. Epub 2012 Jun 5.
PMID: 22674674 [PubMed – indexed for MEDLINE]